17th Fraunhofer seminar Translational Airway Research "Models of Lung Disease"

hosted by Fraunhofer ITEM

Fraunhofer ITEM

Start: 18 Jan 2018

End: 19 Jan 2018

  • Preliminary agenda

    Please note that this page will be updated as required (last updated on Jan 12, 2018).

    Thursday, January 18, 2018

    09:15 Welcome

    Models of COPD

    09:30 Eosinophilic COPD – does it exist?
    Timm Greulich, Marburg, Germany

    10:00 Segmental endotoxin challenge – from conventional inflammatory endpoints to novel imaging markers
    Jens Vogel-Claussen, Hannover, Germany/Jens Hohlfeld, Fraunhofer ITEM, Germany

    10:30 Coffee break

    Models of asthma

    11:00 Metabolic programs regulating immune cell function
    Luciana Berod, Twincore, Germany

    11:30 Biomarkers for monitoring clinical efficacy of allergen immunotherapy
    Carsten Schmidt-Weber, Munich, Germany

    12:00 The all age Asthma Cohort (ALLIANCE) – from early beginnings to chronic disease
    Gesine Hansen/Anna Dittrich, Hannover, Germany

    12:30 Lunch

    Models of lung infection and exacerbation

    13:30 IL-33 drives influenza-induced exacerbation of experimental asthma
    Lara Ravanetti, Amsterdam, The Netherlands

    14:00 Cell therapy of lung infection
    Nico Lachmann, Hannover, Germany

    14:30 Coffee break

    15:00 Rhinovirus-induced immune response in human lung
    Olga Danov, Fraunhofer ITEM, Germany

    Special lecture

    15:30 Lung diseases – what's in the pipeline?
    Siegfried Throm, vfa, Germany

    International Consortium for Anti-Infective Research (iCAIR): official launch ceremony

    16:00 Introduction
    Armin Braun, Fraunhofer ITEM, Hannover

    16:20 Speeches of special guests:
    Margalit Levin, Secondary Secretary of the Australian Embassy, Berlin, Germany
    Thomas Dickert, International Business Development, Fraunhofer-Gesellschaft, Munich, Germany
    Rita Gerardy-Schahn, iCAIR Management Board, Hannover Medical School, Hannover, Germany

    17:00 Development of new anti-infectives
    Mark von Itzstein, Gold Coast, Australia

    17:30 Wine & cheese poster session

    18:30 Awarding of poster prizes

    18:45 Guided tours to Fraunhofer ITEM departments:

    • PCLS
    • Lung function + IPL
    • CRC Hannover
    • In-vitro testing

    19:15 Dinner at the CRC Hannover


    Friday, January 19, 2018

    08:30 Guided tours to Fraunhofer ITEM departments:

    • PCLS
    • Lung function + IPL
    • Pathology
    • CRC Hannover
    • In-vitro testing

    Models of tumor development

    9:00 Models of metastasis formation: new challenges ahead 
    Christoph Andreas Klein, Fraunhofer ITEM, Germany

    9:30 Tumor-microenvironmental factors and their intervention in co-cultures of fresh human lung tissue and patient-derived, disseminated cancer cells
    Sebastian Konzok, Fraunhofer ITEM, Germany

    10:00 Activation of innate immunity results in lung cancer proliferation – role for myeloid cells and epithelial cytokines
    Christoph Beisswenger, Homburg, Germany

    10:30 Oncolytic virotherapy of lung cancer in the era of immunotherapy – a challenge for preclinical models
    Guido Wollmann, Innsbruck, Austria

    11:00 Coffee break

    Models of fibrosis

    11:30 Scientific rationale to develop nintedanib in progressive fibrosing interstitial lung diseases
    Stefan-Lutz Wollin, Boehringer Ingelheim, Germany

    12:00 Understanding IPF disease progression through biomarker efforts
    Maggie Neighbors, Genentech, USA

    12:30 Neoepitope fragments of extracellular matrix as markers of pulmonary fibrosis: Insights into clinical and preclinical utilization for unfolding disease pathogenesis
    Diana Leeming, Nordic Bioscience, Denmark

    13:00 Lunch

    14:00 New humanized in vitro and in vivo models of idiopathic pulmonary fibrosis (IPF)
    Antje Prasse, Fraunhofer ITEM, Germany

    14:30 A story of success: developmental program identifies siRNA HSP47 as a new therapeutic strategy for fibrotic diseases
    Wenbin Ying, Nitto BioPharma, USA

    15:00 Coffee break

    New technologies in lung research

    15:30 Slide-based cytometry
    Meike Müller, Fraunhofer ITEM, Germany

    16:00 Lung pathophysiology in three dimensions: microfluidic human “small airway-on-a-chip” for clinical translation
    Kambez Benam, Colorado, Denver, USA

    16:30 Suitability of sheep for the testing of respiratory delivery technologies and drug formulations
    Robert Bischof, Hudson Institute of Medical Research, Australia

    17:00 Science or fiction? Tracking mouse lung disease and host response through the four dimensions of space and time
    Greetje Vande Velde, Leuven, Belgium

    17:30 End of workshop




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